Researchers at Lund University in Sweden have developed a digital cognitive test for diagnosing Alzheimer’s disease that is intended for use in primary care.
“This digital test, which patients perform on their own with minimal involvement from healthcare personnel, improves the primary care physician’s ability to determine who should be further examined by blood tests for Alzheimer’s pathology early in the investigation phase,” says Professor Oskar Hansson, who led the study alongside Pontus Tideman.
Alzheimer’s disease is the most common cause of dementia. As new disease-modifying treatments for Alzheimer’s disease are now becoming available, both early and accurate diagnosis in a resource-efficient assessment process are becoming increasingly important, as not everyone responds to the new drugs. Seeking medical care for cognitive impairment is not necessarily the result of Alzheimer’s disease – it can for example be caused by depression, fatigue or other dementias.
“Primary care does not have the resources, time or specialist knowledge to investigate possible Alzheimer’s disease in the same way as specialised memory clinics. And this is where a digital cognitive test can make the biggest difference,” says Oskar Hansson, professor of neurology at Lund University.
Unlike pen-and-paper tests, which are generally used to assess cognitive impairment, digital tests provide a more detailed picture. More aspects and new variables that could not previously be measured as easily are included.
“The vast majority of people who experience memory loss will first seek treatment at their health centre. Our new digital test provides a first objective picture – at an earlier stage and with greater precision – of which patients have cognitive impairment indicative of Alzheimer’s disease. This indicates who should proceed with the blood test that measures the level of phosphorylated tau and is able to detect Alzheimer’s pathology in the brain with high accuracy,” says Pontus Tideman, doctoral student in the research group, Clinical Memory Research at Lund University and psychologist at the Memory Clinic, Skåne University Hospital.
Read full press release on Lund University´s webpages