Register for Pharmaron’s Webinar on Macrocycles in Drug Design
Macrocycles: An Increasingly Popular Strategy in Drug Design
Join us for an in-depth exploration of macrocycles in drug design and discovery!
In this webinar, Mike Waring, Professor and Head of Medicinal Chemistry at Newcastle University, and Sébastien Campos, Senior Director of Medicinal Chemistry at Pharmaron, will explore how macrocycles are transforming the field.
Discover key principles for rational macrocycle design and learn about the unique benefits and challenges of this compound class
This webinar will review the emergence of macrocycles as a powerful strategy in drug design and discovery, highlighting the principles of rational design and the benefits and challenges of this class of compounds.
Agenda:
- Introductions to macrocycles
What are macrocyclic drugs?
What are their advantages compared to their acyclic counterparts?• Macrocycle rational design
What are the strategies to design successful macrocycles?
What are the known principles for the optimization of physicochemical properties? - Case Study: the discovery of a novel series of PKCθ inhibitors with exquisite potency and isoform selectivity
Success and challenges throughout the lead optimization process.
Date: 5th December 2024
Time: 8am PT/ 11am ET/ 4pm GMT / 5pm CET
Venue: Online webinar